Efeito de nanopartículas de óxido de ferro funcionalizadas com ácido cítrico no crescimento de Pseudomonas aeruginosa

Abstract

Nanomaterials have unique properties related to their size. For this reason, nanotechnology has attracted much attention from the scientific community. Iron oxide nanomaterials have been used for various purposes including cosmetics, paints, plastics, textiles and even as antimicrobial agents against pathogenic bacteria. Iron oxide nanoparticles were synthesized by coprecipitation, functionalized with citric acid and characterized by X-ray diffraction, infrared spectroscopy, flame atomic absorption spectroscopy, zeta potential and transmission electron microscopy. As well as determined the median lethal dose by the microcrack Artemia salina and evaluated the antimicrobial activity of these nanomaterials against bacteria Pseudomonas aeruginosa. Iron oxide nanoparticles functionalized and iron oxide nanoparticles no functionalized had a mean diameter of 10 nm, and iron ion concentration per mL of 23 for iron oxide nanoparticles functionalized and 7 mg of ions for iron oxide nanoparticles no functionalized as well as surface charge of +33 and -9 mV, respectively, by zeta potential. Both iron oxide nanoparticles were no toxic for the median lethal determination test for Artemia salina and showed an antimicrobial effect against Pseudomonas aeruginosa bacteria, observed in the mean inhibition of about 7.0.104 CFU.mL-1 of the growth of these bacteria in deionized water and in trypticasein soy broth medium . This way it shows to be effective antimicrobial agents and can be considered an innovative alternative against the development of Pseudomonas aeruginosa